Sunday, October 13, 2013

Marijuana Compound Induces Cell Death In Hard To Treat Brain Cancer

Madrid, Spain: The combined administration of THC and the pharmaceutical agent temozolomide (TMZ) demonstrates strong anti-cancer activity in brain tumors resistant to conventional anti-cancer treatments, according to preclinical data published online in the journal Molecular Cancer Therapeutics.

Investigators at Complutense University in Spain assessed the anti-tumor activity of the cannabinoids THC and CBD (cannabidiol) in glioma xenografts (tissue grafts).

Authors reported that the administration of THC in combination with TMZ (the benchmark agent for the management of glioblastoma) "enhanced autophagy" (programmed cell death) in malignant tissue. The combined administration of THC, CBD, and TMZ "remarkably reduce[d] the growth of glioma xenografts ... [and] produced a strong antitumoral action in both TMZ-sensitive and TMZ-resistant tumors."........

You can read the full story here

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